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In particular, fibroblasts exhibit a high degree of plasticity and are able to differentiate from fusiform progenitors into polygonal fibroblasts and myofibroblasts with strong contractile capacity, a process that is carefully regulated by mechanical signals, cytokines and growth factors (especially transforming growth factor-β, TGF-β)

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The dermis of peptide-treated skin also lacked neutrophils (not shown)